Rick Russell
University of Texas at Austin, USA
Biography
Rick Russell has expertise in quantitative biochemical and biophysical approaches to dissect the activities of enzymes that manipulate RNA and DNA structures. Work from his lab has focused on RNA helicase proteins that function as chaperones in the complex tertiary folding processes of structured RNAs, and additional research has increased our understanding of the folding mechanisms of these RNAs. Recent work from the lab has also included a focus on DHX36, a human helicase protein that efficiently disrupts G-quadruplex structures in DNA and RNA.
Abstract
Abstract : Kinetic basis for DNA target specificity of CRISPR-Cas12a