Nucleic Acids

Computational Molecular Biology

Computational molecular biology is a field which unites statistical, computational, technological & experimental methods, which is energizing & vividly accelerating the discovery of new technologies & tools for molecular biology. It deals with the main issues concerning analysis of sequences, genomes and structures. This introduces the simple computational methods used to understand the cell on a molecular level. It covers subjects such as the sequence alignment algorithms: hashing, dynamic programming, suffix trees, and Gibbs sampling. Furthermore, it focuses on computational approaches to: genetic & physical mapping; genome sequencing, assembly & annotation; RNA expression & secondary structure; protein structure & folding; and molecular interactions & dynamics.