Nucleic Acids

Molecular Therapeutics

Nucleic acids Therapeutics  encompass a vast array of approaches with a set of key considerations based on their size and mechanism of action like aptamers, antisense, small interfering RNA (siRNA), exon skipping, RNA editing. Medicinal promise of pre transcription & post- transcriptional gene silencing (PPTGS) using oligodeoxynucleotides, small interfering RNA, microRNA and other nucleic acid based molecules can be developed into effective drugs for the treatment of many common diseases that are generally responsible for a great deal of human suffering. Numerous types of cancer are known to have abnormal genes that are useful in disease states. These genes are attractive targets to approach for treatment of wide range of cancers. In different experimental systems nucleic-acid-based molecules have been shown to be very effective tools for adjusting gene expression in a sequence specific manner. Thereby they appear to be one of the most promising cancer therapeutics. They are more specialized and low toxic than conventional chemotherapy.